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Description:
Cefixim®is a broad spectrum, third generation oral Cephalosporin antibiotic for oral use. It is a bactericidal and is stable to hydrolysis by beta-lactamases. The drug kills bacteria by interfering with the synthesis of bacterial cell wall. It is highly effective against most Enterobacteriaceae, Haemophilus influenzae, Neisseria gonorrhoeae, -haemolytic Streptococcus and Streptococcus pneumoniae.
About 65% of the drug in thecirculation is bound to plasma protein. Cefixim® is mainly excreted unchanged in bile and urine.
Cefixim®is a broad spectrum, third generation oral Cephalosporin antibiotic for oral use. It is a bactericidal and is stable to hydrolysis by beta-lactamases. The drug kills bacteria by interfering with the synthesis of bacterial cell wall. It is highly effective against most Enterobacteriaceae, Haemophilus influenzae, Neisseria gonorrhoeae, -haemolytic Streptococcus and Streptococcus pneumoniae.
About 65% of the drug in thecirculation is bound to plasma protein. Cefixim® is mainly excreted unchanged in bile and urine.
Composition:
Cefixim®Capsule : Each capsule contains Cefixime trihydrate USP, equivalent to Cefixime USP 200 mg.
Cefixim®Dry Suspension : Each 5 ml suspension (reconstituted from Dry Syrup) contains Cefixime trihydrate USP, equivalent to Cefixime USP 100 mg.
Cefixim®Capsule : Each capsule contains Cefixime trihydrate USP, equivalent to Cefixime USP 200 mg.
Cefixim®Dry Suspension : Each 5 ml suspension (reconstituted from Dry Syrup) contains Cefixime trihydrate USP, equivalent to Cefixime USP 100 mg.
Indication:
Cefixim®is indicated in the treatment of following acute infections caused by susceptible microorganisms:
Upper respiratory tract infection (URTI) : Otitis media and others where causative organisms are known or suspected to be resistant to other commonly used antibiotics or where treatment failure may carry significant risk.
Lower respiratory tract infection (LRTI) : Bronchitis.
Gastrointestinal tract infection (GITI) : Typhoid fever.
Urinary tract infection (UTI): Cystitis, cystourethritis, pyelonephritis.
Cefixim®is indicated in the treatment of following acute infections caused by susceptible microorganisms:
Upper respiratory tract infection (URTI) : Otitis media and others where causative organisms are known or suspected to be resistant to other commonly used antibiotics or where treatment failure may carry significant risk.
Lower respiratory tract infection (LRTI) : Bronchitis.
Gastrointestinal tract infection (GITI) : Typhoid fever.
Urinary tract infection (UTI): Cystitis, cystourethritis, pyelonephritis.
Dosage and administration :
With Cefixim®the usual course of treatment is 7 days. This may be continued up
to 14 days.
Adults & Children over 10 years old: The recommended adult dosage is 1-2 capsule (200-400 mg) daily according to the severity of infection, given in either as a single dose or in two divided doses.
Elderly: Elderly patients may be given the same dose as recommended for the adults. Renal functions should be assessed and dosage should be adjusted in severe renal impairment.
Children : The recommended dosage for children is 8 mg/kg/day administered as single dose or in two divided dose.
As a general guide the following daily doses are suggested:
Cefixim®
Children (6-12 months) : Suspension 3.75 ml (75 mg) daily.
Children (1-4 years) : Suspension 5 ml (100 mg) daily.
Children (5-10 years) : Suspension 10 ml (200 mg) daily.
Children weighing more than 50 kg or older than 10 years : Adult dose of Cefixim®(200-400 mg daily) is recommended.
Adults & Children over 10 years old: The recommended adult dosage is 1-2 capsule (200-400 mg) daily according to the severity of infection, given in either as a single dose or in two divided doses.
Elderly: Elderly patients may be given the same dose as recommended for the adults. Renal functions should be assessed and dosage should be adjusted in severe renal impairment.
Children : The recommended dosage for children is 8 mg/kg/day administered as single dose or in two divided dose.
As a general guide the following daily doses are suggested:
Cefixim®
Children (6-12 months) : Suspension 3.75 ml (75 mg) daily.
Children (1-4 years) : Suspension 5 ml (100 mg) daily.
Children (5-10 years) : Suspension 10 ml (200 mg) daily.
Children weighing more than 50 kg or older than 10 years : Adult dose of Cefixim®(200-400 mg daily) is recommended.
Pecaution:
In presence of impaired renal function Cefixim®should be administered with caution. In patient creatinine clearance less than 20 ml/min, it is recommended that a dose of 200 mg once daily should not be exceeded.
In presence of impaired renal function Cefixim®should be administered with caution. In patient creatinine clearance less than 20 ml/min, it is recommended that a dose of 200 mg once daily should not be exceeded.
Use in Pregnancy and Lactation:
Cefixim®should not be used in pregnancy or nursing mother unless considered essential by the physician.
Side
effect:
Cefixim®is generally well tolerated. The majority of adverse reactions observed are mild and self-limiting in nature. GIT disturbances : Diarrhoea and changes in stool colour, nausea, abdominal pain, dyspepsia, vomiting and flatulence. CNS disturbances: Headache and dizziness. Hypersensitivity reactions: Rash, pruritus, urticaria, drug fever and arthralgia have been observed.
Cefixim®is generally well tolerated. The majority of adverse reactions observed are mild and self-limiting in nature. GIT disturbances : Diarrhoea and changes in stool colour, nausea, abdominal pain, dyspepsia, vomiting and flatulence. CNS disturbances: Headache and dizziness. Hypersensitivity reactions: Rash, pruritus, urticaria, drug fever and arthralgia have been observed.
Contraindication:
Cefixim®is contraindicated in patients with known hypersensitivity to Cephalosporin group of drugs.
Cefixim®is contraindicated in patients with known hypersensitivity to Cephalosporin group of drugs.
How
supplied:
Cefixim® Capsule : Box contains 1 x 5’s capsules in blister pack.
Cefixim® Dry Suspension : Bottle contains dry powder for 50 ml suspension.
Manufacturer’s Source: IBN SINA
Cefixim® Capsule : Box contains 1 x 5’s capsules in blister pack.
Cefixim® Dry Suspension : Bottle contains dry powder for 50 ml suspension.
Manufacturer’s Source: IBN SINA
One of the top 10 companies to manufacture "THE STABLE AMOXYCILLIN CLAVULANIC ACID FORMULATIONS" and one of the leading Indian pharma manufacturers.It offers contract manufacturing, development, and distribution facilities around the world and is a cefditoren pivoxil ,cephalexin, cefixime manufacturer ,along with some other products.The Quality control system is an ongoing process which assures preventive or remedial efforts.
ReplyDeleteCefixime is an antibiotic useful to treat a number of bacterial infections.It treats infections of the ear,sinuses,throat,etc.Cefixime manufacturers in India always sugest you to ask your doctor before having it for the safety side.Cefixime is in a class of medications called cephalosporin along with other products like Cefetamet Pivoxil,Ceftibuten,cefditoren pivoxil etc.
ReplyDeleteCefixime is an antibiotic and is used to treat a number of bacterial infections and to stop the growth of bacteria. Cefixime manufacturer Companies should always try to match up the demand and varying needs of customers.It will not work for viral infections. Antibiotics manufacturers Companies should know that although cefixime is an effective antibiotic in many situations, less expensive and equally effective alternatives are frequently available.
ReplyDeleteCefixime is an antibiotic that works by stopping the growth of bacteria. This medication is known as a cephalosporin antibiotic.Cefixime manufacurer and supplier must provide the clients with Premium quality, Highly effective, and superior effectivenes.
ReplyDeleteCefixime is an antibiotic useful to treat a number of bacterial infections.It treats infections of the ear,sinuses,throat,etc
ReplyDeleteantibiotic
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