Aerovil - Pheniramine Maleate Syrup

Aerovil^® is a preparation of Pheniramine, which is a competitive H₁ histamine receptor antagonist.It is indicated in hay fever and perennial rhinitis, vasomotor rhinitis,mild uncomplicated allergic skin reactions like dermatitis, eczema, urticaria, angioedema,pruritis and vertigo.

® time tested antihistamine

       §  Exhibits strong antihistamine activity 

  §  Guarantees confident relief from allergic symptoms 

       §  Cures rhinitis and make the life easier

  §  Assures compliance for pediatric patients

Description:

Pheniramine is a competitive H₁ histamine receptor antagonist. Like other alkylamine antihistamines it is also antagonist of muscarinic cholinergic receptors and possesses local anesthetic properties. However, the concentration required for the latter effect is probably not achieved at therapeutic dose.

Indications:

Pheniramine is indicated in hay fever and perennial rhinitis, vasomotor rhinitis, mild uncomplicated allergic skin reactions like dermatitis, eczema, urticaria, angioedema and pruritis, and vertigo.lt has also been used for its antiemetic properties in the prevention and control of motion sickness.

Dosage and Administration:

Children:

Syrup is particularly preferable for children. 1-3 years : 1/2 a measuring spoonful (7.5 mg) 2-3 times daily.

4-12 years : 1 measuring spoonful (15 mg) 2-3 times daily.

Adult:

Adults and children over 12 years : 1-2 measuring spoonful (15-30 mg) 2-3 times daily.

Side Effects:

The most common side effect is sedation that varies from slight drowsiness to deep sleep. Inability to concentrate, lassitude, dizziness, muscular weakness and incoordination may also occur. Other side effects are headache, dry mouth, constipation, blurred vision, etc.

Precautions:

If drowsiness, patients should not drive or operate machinery requiring alertness. Alcohol and certain other CNS depressants can potentiate the sedative effects of antihistaminic and patient should be warned of these effects.

Contraindications:

Pheniramine is contraindicated with known hypersensitivity to pheniramine. New born and premature infants are also contraindicated as it may act as a CNS stimulant.

Use in Pregnancy and Lactation: Pheniramine is contraindicated in pregnancy since safety of pheniramine has not been thoroughly studied. The drug is not recommended during breast feeding, although the concentration achieved in the breast milk are unlikely to be of clinical significance.

Pharmaceutical Precautions:

Store in a cool, dry place, away from light. Keep out of reach of children.

Commercial Pack:

Aerovil® Syrup : Bottle containing 100 ml syrup. Each 5 ml contains Pheniramine Maleate BP15 mg.

Source and Manufactured by

BEXIMCOPHARMACEUTICALS LTD.

TONGI, BANGLADESH

® REGISTERED TRADEMARK